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Because of the highly conserved nature of UCEs and their flanking sequence, we have found these probes work well across fishes.Get 2,001 probe set for fish » Below are several software packages we have developed to help analyze data collected from UCE loci.Report an issue with illumiprocessor Get illumiprocessor » A program started by Nick Crawford with contributions from Brant Faircloth for parallel computation of individual genetrees and the estimation of a species tree from gene tree data.Allows analysis and bootstrapping of large datasets.
Many of the steps, at this point, require that you are comfortable working with computer software on the command line. MYcroarray has even made a discounted "pilot" sized kit available for labs who want to do some test enrichments.
We have several larger probes sets in the works for fishes, and we are also working on optimizing probe sets based on their capture success, phylogenetic utility, etc. You can now buy this probe set direct from MYcroarray in the form of a capture kit.
MYcroarray has even made a discounted "pilot" sized kit available for labs who want to do some test enrichments.
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As their name implies, ultraconserved elements (UCEs) are highly conserved regions of organismal genomes shared among evolutionary distant taxa - for instance, birds share many UCEs with humans.